Metabolomics Core Unit

    Publikationen

    2017

    Fuchs, B., Breuer, T., Krischke, M., Mueller, M.J., Findling, S., Holzschuh, A., Krauss, J. (2017) Enhanced aphid abundance in spring desynchronizes predator-prey and plant microorganism interactions.
    Oecologia, 183, 469-478.

    Fuchs, B., Krischke, M., Mueller, M.J., Krauss, J. (2017) Herbivore-specific induction of defence metabolites in a grass-endophyte association.
    Functional Ecology, 31, 318-324.

    2016

    Blättner, S., Das, S., Paprotka, K., Eilers, U., Krischke, M., Kretschmer, D., Remmele, C.W., Dittrich, M., Mueller, T., Schuelein-Voelk, C., Hertlein, T., Mueller, M.J., Huettel, B., Reinhardt, R., Ohlsen, K., Rudel, T., Fraunholz, M.J. (2016) Staphylococcus aureus Exploits a Nonribosomal Cyclic Peptide to Modulate Survival within Epithelial Cells and Phagocytes.
    PLOS Pathogens, 12, e1005857.

    Segerer, G., Hadamek, K., Zundler, M., Fekete, A., Seifried, A., Mueller, M.J., Koentgen, F., Gessler, M., Jeanclos, E., Gohla, A. (2016) An essential developmental function of murine phosphoglycolate phosphatase in safeguarding cell proliferation.
    Sci Rep., 6, 35160.

    Ruemer, S., Krischke, M., Fekete, A., Lesch, M., Mueller, M.J., Kaiser, W.M. (2016) Methods to Detect Nitric Oxide in Plants: Are DAFs Really Measuring NO?
    Methods Mol Biol., 1424, 57-68.

    Cheng, C., Othman, E.M., Fekete, A., Krischke, M., Stopper, H., Edrada-Ebel, R., Mueller, M.J., Hentschel, U., Abdelmohsen, U.R. (2016) Strepoxazine A, a new cytotoxic phenoxazin from the marine sponge-derived bacterium Streptomyces sp. SBT345.
    Tetrahedron Letters, 57, 4196-4199.

    Leide, J., Hansjakob, A., Forster, F., Fekete, A., Csilléry, G., Erós-Honti, Z., Riederer, M. (2016) Cutin deficiency of bell pepper (Capsicum annuum L.) results in gluey berries.

    Fräbel, S., Krischke, M., Staniek, A., Warzecha, H. (2016) Recombinant flavin-dependent halogenases are functional in tobacco chloroplasts without coexpression of flavin reductase genes.
    Biotechnology Journal, 11, 1586-1594.


    2015

    Hartmann, L., Pedrotti, L., Weiste, C., Fekete, A., Schierstaedt, J., Göttler, J., Kempa S., Krischke, M., Dietrich, K., Müller, M.J., Vicente-Carbajosa, J., Hanson, J., Dröge-Laser, W. (2015) Crosstalk between two basic leucine ZIPPER signaling pathways orchestrates salt-induced metabolic reprogramming in Arabidopsis roots.
    Plant Cell, 27, 2244-2260.

    Mueller, S.P., Krause, D.M., Mueller, M.J., Fekete A. (2015) Accumulation of extra-chloroplastic triacylglycerols in Arabidopsis seedlings during heat acclimation.
    J Exp Bot.
    , 66, 4517-26.

    Muelek, M., Fekete, A., Wiest, J., Holzgrabe, U., Mueller, M.J., Hoegger P (2015) Profiling a gut microbiota-generated catechin metabolite's fate in human blood cells using a metabolomic approach.
    J
    Pharm Biomed Anal., 114, 71-81.

    Ahmed, Z., Mayr, M., Zeeshan, S., Dandekar, T., Mueller, M.J., Fekete A (2014) Lipid-Pro: a computational lipid identification solution for untargeted lipidomics on data-independent acquisition tandem mass spectrometry platforms.
    Bioinformatics, 31, 1150-1153.

    Awad, J., Stotz, H., Fekete, A., Krischke, M., Engert, C., Havaux, M., Berger, S., Mueller, MJ. (2015) 2-Cys peroxiredoxins and thylakoid ascorbate peroxidase create a water-water cycle that is essential to protect the photosynthetic apparatus under high light stress conditions.
    Plant Physiol., 167, 1592-1603.


    2014

    Klinkenberg, J., Faist, H., Saupe, S., Lambertz, S., Krischke, M., Stingl, N., Fekete, A., Mueller, M.J., Feussner, I., Hedrich, R., Deeken, R. (2014) Two fatty acid desaturases, STEAROYL-ACYL CARRIER PROTEIN Δ9-DESATURASE6 and FATTY ACID DESATURASE3, are involved in drought and hypoxia stress signaling in Arabidopsis crown galls.
    Plant Physiol., 164, 570-583.

    Scholl, C., Wang, Y., Krischke, M., Mueller, M.J., Amdam, G.V., Rössler, W. (2014) Light exposure leads to reorganization of microglomeruli in the mushroom bodies and influences juvenile hormone levels in the honeybee.
    Dev Neurobiol., 74, 1141-53.


    2013

    Schiebel, J., Kapilashrami, K., Fekete, A, Bommineni, G.R., Schaefer, C.M., Mueller, M.J., Tonge, P.J., Kisker, C. (2013) Structural Basis for the Recognition of Mycolic Acid Precursors by KasA, a Condensing Enzyme and Drug Target from Mycobacterium Tuberculosis.
    J. Biol. Chem., 288, 34190-34204.

    Findling, S., Fekete, A. ,Warzecha, H., Krischke, M., Brandt, H., Blume, E., Mueller, M.J., Berger, S. (2013) Manipulation of methyl jasmonate esterase activity renders tomato more susceptible to Sclerotinia sclerotiorum.
    Functional Plant Biology, 41,133-143.

    Boca, S., Koestler, F., Ksas, B., Chevalier, A., Leymarie, J., Fekete, A., Mueller, MJ., Havaux, M. (2013) Arabidopsis lipocalins AtCHL and AtTIL have distinct but overlapping functions essential for lipid protection and seed longevity.
    Plant Cell Environ., 37,368-381.

    Leikam, C., Hufnagel, A., Walz, S., Kneitz, S., Fekete, A., Müller, M.J., Eilers, M., Schartl, M., Meierjohann, S. (2014) Cystathionase mediates senescence evasion in melanocytes and melanoma.
    Oncogen, 33, 771-782.

    Fuchs, B., Krischke, M., Mueller, M.J., Krauss, J. (2013) Peramine and Lolitrem B from endophyte-grass associations cascade up the food chain.
    J. Chem. Ecol. 39, 1385-1389.

    Pedrotti, L., Mueller, M.J., Waller, F. (2013) Piriformospora indica root colonization triggers local and systemic root responses and inhibits secondary colonization of distal roots.
    PLoS One 8(7):e69352.doi:10.1371/journal.pone.0069352.

    Ramel, F., Ksas, B., Akkari, E., Mialoundama, A.S., Monnet, F., Krieger-Liszkay, A., Ravanat, J-L., Mueller, M.J., Bouvier, F., Havaux, M. (2013) Light-induced acclimation of the Arbabidopsis chlorina1 mutant to singlet oxygen.
    Plant Cell, 25, 1445-1462.

    Grebner, W., Stingl, N.E., Oenel, A., Mueller, M.J., Berger, S. (2013) Lipoxygenase 6-dependent Oxylipin Synthesis in Roots is required for abiotic and biotic Stress Resistance of Arabidopsis thaliana.
    Plant Physiol., 161, 2159-2170.

    Stingl, N., Krischke, M., Fekete, A., Mueller, M.J. (2013) Analysis of defense signals in Arabidopsis thaliana leaves by ultra performance liquid chromatography/ tandem mass spectrometry: jasmonates, salicylic acid, abscisic acid.
    Methods Mol. Biol., 1009, 103-113.


    2012

    Zoeller, M., Stingl, N., Krischke, M., Fekete, A., Waller, F., Berger, S., Mueller, M.J. (2012) Mechanisms and targets of lipid oxidation in the incompatible Pseudomonas-Arabidopsis interaction: Biogenesis of azelaic and pimelic acid.
    Plant Physiol., 160, 365-78.

    Ott, C., Ross, K., Straub, S., Thiede, B., Götz, M., Goosmann, C., Krischke, M., Mueller, M.J., Krohne, G., Rudel, T., Kozjak-Pavlovic, V. (2012) Sam50 functions in mitochondrial intermembrane spage bridging and biogenesis of respiratory complexes.
    Mol. Cell. Biol., 32, 1173-1188.

    Rümer S., Krischke M., Fekete A., Mueller M.J., Kaiser W.M. (2012) DAF-fluorescence without NO: Elicitor treated tobacco cells produce fluorescing DAF-derivatives not related to DAF-2 triazol.
    Nitric Oxide 27,123-135.


    2011

    Stotz, H.U., Sawada, Y., Shimada, Y., Hirai, M.Y., Sasaki, E., Krischke, M., Brown, P.D., Saito, K., Kamiya, Y. (2011) Role of camalexin, indole glucosinolates, and side chain modifications of glucosinolate-derived isothiocyanates in defense of Arabidopsis against Sklerotinia sclerotiorum.
    Plant J., 67, 81-93.

    Stotz, H.U., Jikumaru, Y., Shimada, Y., Y., Sasaki, E., Stingl, N., Mueller, M.J., Kamiya, Y. (2011) Jasmonate-dependent and COI1-independent defense responses against Sclerotinia sclerotium in Arabidopsis thaliana: Auxin is part of COI1-independent defense signalling.
    Plant Cell Physiol., 52, 1941-1956.

    Peer, M., Bach, M., Mueller, M.J., Waller, F. (2011) Free sphingobases induce RBDOHD-dependent reactive oxygen species production in Arabidopsis thaliana leaves.
    FEBS Lett., 585, 3006-3010.

    Birtic, S., Ksas, B., Genty, B., Mueller, M.J., Triantaphylidès, C., Havaux, M. (2011) Using spontaneous photon emission to image lipid oxidation patterns in plant tissues.
    Plant J., 67, 1103-1115.

    Sogabe, Y., Nakamura, H., Nagakawa, T., Hasegawa, S., Asano, T., Ohta, H., Yamaguchi, K., Mueller, M.J., Kodama, H., Nishiuchi, T. (2011) Visualization of Wounding-induced Root-to-Shoot Communication in Arabidopsis.
    Plant Signal Behav., 6, 1057-1039.

    Hasegawa, S., Sogabe, Y., Asanao, T., Nakagawa, T., Nakamura, H., Kodama, H., Ohta, H., Yamaguchi, K., Mueller, M.J., Nishiuchi, T. (2011) Gene expression analysis of wounding-induced root-to-shoot communication in Arabidopsis thaliana.
    Plant Cell Environ., 34, 705-716.


    2010

    Peer, M., Stegmann, M., Mueller, M.J., Waller, F. (2010) Pseudomonas syringae infection triggers de novo synthesis of phytosphingosine from sphinganine in Arabidopsis thaliana.
    FEBS Lett., 584, 4053-4056.

    Ellinger, S., Stingl, N.E., Kubigsteltig, I.I., Bals, T., Juenger, M., Pollmann, S., Berger, S., Schünemann, D., Mueller, M.J. (2010) DGL and DAD1 lipases are not essential for wound- and pathogen-induced jasmonate biosynthesis: redundant lipases contribute to jasmonate formation.
    Plant Physiol., 153, 114-127.

    Seltmann, M.A., Stingl, N.E., Lautenschlaeger, J.,K., Krischke, M., Mueller, M.J., Berger, S. (2010) Differential impact of lipoxygenase 2 and jasmonates on natural and stress-induced senescence in  Arabidopsis thaliana.
    Plant Physiol., 152, 1940-1950.

    Bruinsma, M., van Broekhoven, S., Poelman, E.H., Posthumus, M.A., Mueller, M.J., van Loon, J.J., Dicke, M. (2010) Inhibition of lipoxygenase affects induction of both direct and indirect plant defences against herbivorous insects.
    Oecologia, 162, 293-404.

    Gilles, S., Jacoby, D., Blume, C., Mueller, M.J., Jakob, T., Behrendt, H., Schaekel, K., Traidl-Hoffmann, C. (2010) Pollen-derived low-molecular weight factors inhibit 6-sulfo LacNAc1 dendritic cells' capacity to induce T-helper type 1 responses.
    Clin. Exp. All. 40, 269-278.


    2009

    Gilles, S., Mariani, V., Bryce., M., Mueller, M.J., Ring, J., Behrendt, H., Jakob, T., Traidl-Hoffmann, C. (2009) Pollen allergens do not come alone: pollen associated lipid mediators (PALMS) shift the human immue systems towards a Th2-dominated response.
    Allergy, Asthma & Clin. Immun. 5, 3.

    Durand, T., Bultel-Poncé, V., Guy, A., Berger, S., Mueller, M.J., Galano, J.-M. (2009) New Bioactive Oxylipins Formed by Non-enzymatic Free-Radical-Catalyzed Pathways: The Phytoprostanes.
    Lipids 44, 875-878.

    Berger, S., Mueller, M.J. (2009) Reactive electrophilic oxylipins: Pattern recognition and signaling.
    Phytochemistry 70, 1511-1521.

    Barden, A.E., Croft, K.D., Durand, T., Guy, A., Mueller, M.J., Mori, T.A. (2009) Flaxseed oil supplementation increases F1-phytoprostanes in healthy men.
    J. Nutrition 139, 1890-1895.

    Gilles, S., Mariani, V., Bryce, M., Mueller, M.J., Ring, J., Jakob, T., Pastore, S., Behrendt, H., Traidl-Hoffmann, C. (2009) Pollen derived E1-phytoprostanes signal via PPARg and NF-kB dependent mechanisms.
    J. Immunol. 182, 6653-6658.

    Bruinsma, M., Posthumus, M.A., Mumm, R., Mueller, M.J., van Loon, J.J.A., Dicke, M. (2009) Jasmonic acid-induced volatiles of Brassica oleracea attract parasitoid: effects of time, dose and comparison with induction by herbivores.
    J. Exp. Bot. 60, 2575-2587.
    Comment: Wasternack, C., Hause, B. (2009) Emerging complexity: jasmonate induced volatiles affect paraitoid choice.
    J. Exp. Bot. 60, 2451-2453.

    Yarali, A., Krischke, M., Michels, B., Saumweber, T., Mueller, M.J., Gerber, B. (2009)
    Genetic distortion of the balance between punishment and relief learning in Drosophila.
    J. Neurogenet. 23, 235-247.
     

    2008

    Dueckershoff, K., Mueller, S., Mueller, M.J., Reinders, J. (2008) Impact of cyclopentenone-oxylipins on the proteome of Arabidopsis thaliana.
    Biochim. Biophys. Acta (Proteins and Proteomics) 1784, 1975-1985.

    Triantaphylides, C., Krischke, M., Hoeberichts, F.A., Ksas, B., Gresser, G., Havaux, M., Van Breusegem, F., Mueller, M.J. (2008) Singlet oxygen is the major reactive oxygen species involved in photo-oxidative damage to plants.
    Plant Physiol. 148, 960-968.

    Randolt K., Gimple, O., Geißendörfer, J., Reinders, J., Prusko, C., Mueller, M.J., Albert, S., Tautz, J., Beier, H. (2008) Immune-related proteins induced in the hemolymph after aseptic and septic injury differs in honey bee worker larvae and adults.
    Arch. Insect Biochem. Physiol. 69, 155-167.

    Mueller, S., Hilbert, B., Dueckershoff, K., Roitsch, T., Krischke, M., Mueller, M.J., Berger, S. (2008) General detoxification and stress responses are mediated by oxidized lipids through TGA transcription factors in Arabidopsis.
    Plant Cell 20, 768-785.
    Comment: Eckhardt, N.A. (2008) Oxylipin signaling in plant stress responses.
    Plant Cell 20, 495-497.
     

    2007

    Feldhaar, H., Straka, J., Krischke, M., Berthold, K., Stoll, S., Mueller, M.J., Gross, R. (2007) Nutritional upgrading for omnivor carpenter ants by the endosymbiont Blochmania.
    BMC Biology 5, 48.

    Efetova, M., Zeier, J., Riederer, M., Lee, C.W., Stingl, N., Mueller, M.J., Hartung, W, Hedrich, R., Deeken, R.  (2007) A central role of ABA in drought stress protection of Agrobacterium-induced  tumors on Arabidopsis.
    Plant Physiol. 145, 853-862.

    Schoenleben, S., Sickmann, A., Mueller, M.J., Reinders, J. (2007) Proteome analysis of Apis mellifera royal jelly.
    Anal. Bioanal. Chem. 389, 1087-1093.

    Arts, M.J., Grun, C., de Jong, R.L., Voss, H.-P., Bast, A., Mueller, M.J., Haenen, G.R. (2007) Oxidative degradation of lipids during mashing.
    J. Agric. Food Chem. 22, 7010-7014.

    Mariani, V., Gilles, S., Jakob, T., Thiel, M., Mueller, M.J., Ring, J., Behrendt, H., Traidl-Hoffmann, C. (2007) Immunomodulatory mediators from pollen enhance the migratory capacity of dendritic cells and licence them for Th2 attraction.
    J. Immunol. 178, 7623-7631.

    Gutermuth, J., Bewersdorff, M., Traidl-Hoffmann, C., Ring J., Mueller, M.J., Behrendt, H., Jakob, T. (2007) Immunomodulatory effects of aqueous birch pollen extracts and phytoprostanes on primary immune responses in vivo.
    J. Allergy Clin. Immunol. 120, 293-299.

    Grun, C., Berger, S., Matthes, D., Mueller, M.J. (2007) Early accumulation of non-enzymatically synthesized oxylipins in Arabidopsis thaliana after infection with Pseudomonas syringae.
    Funct. Plant Biology 34, 1-7.

    Berger, S., Benediktyova,  Z., Matous, K., Bonfig,  K., Mueller,  M.J., Nedbal,  L., Roitsch, T. (2007) Visualization of dynamics of plant-pathogen interaction by novel combination of chlorophyll fluorescence imaging and statistical analysis: differential effects of virulent and avirulent strains of P. syringae and of oxylipins on A. thaliana.
    J. Exp. Bot.
    58, 797-806.

    Karg, K., Dirsch, V., Vollmar, A.M., Cracowski, J.-L., Laporte, F., Mueller, M.J. (2007) Biologically active oxidized lipids (phytoprostanes) in the plant diet and parenteral nutrition.
    Free Rad. Res. 41, 25-37.

     
    2006

    Sattler, S.E., Mene-Saffrane, L., Farmer, E.E., Krischke, M., Mueller, M.J., DellaPenna, D. (2006) Non-enzymatic lipid peroxidation reprograms gene expression and activates defense markers in tocopherol deficient mutants.
    Plant Cell 18, 3706-3720.

    Deeken, R., Engelmann, J.C., Efetova, M., Czirjak, T., Müller, T., Kaiser, W.M., Tietz, O., Krischke, M., Mueller, M.J., Palme, K., Dandekar, T., Hedrich, R. (2006) An Integrated View of Gene Expression and Solute Profiles of Arabidopsis Tumors: A Genome-Wide Approach.
    Plant Cell 18, 3617-3634.

    Raake, I., Mueller, M.J., Berger, S. (2006) Defects in allene oxide synthase and OPDA reductase alter the resistance to Pseudomonas syringae and Botrytis cinerea.
    J. Phytopath. 154, 740-744.

    Raake, I., v. Rad, U., Mueller, M.J., Berger, S. (2006) Yeast increases resistance in Arabidopsis against Pseudomonas syringae and Botrytis cinerea by plant-dependent as well as plant independent mechanism.
    Mol. Plant Microbe Interaction 19, 1138-1146.

    Mueller, M.J., Laurent, M.-S., Grun, C., Karg, K., Farmer, E.E. (2006) Oxylipin analysis.
    Plant J. 45, 472-489.

     
    2005

    De Vos, M., Van Oosten, V.R., Van Poecke, R.M.P., Van Pelt, J.A., Pozo, M.J., Mueller, M.J., Buchala, A.J., Métraux, J.-P., Van Loon, L.C., Dicke, M., Pieterse, C.M.J.  (2005) Signal signature and transcriptome changes of Arabidopsis during pathogen and insect attack.
    Mol. Plant-Microbe Interact. 18, 923-937.

    Traidl-Hoffmann, C., Mariani, V., Hochrein, H., Karg, K., Wagner, H., Ring, J., Mueller, M.J., Jakob, T., Behrendt, H. (2005) Pollen associated phytoprostanes inhibit dendritic cell IL-12 production and augment Th2 cell polarization.
    J. Exp. Med. 201, 627-636. (Highlight article).
    Comments: Pollen polarize dentritic cells (2005) J.Exp.Med. 201: 486; Pollen power (2005) Nat. Med. 11: 259; Allergic oil (2005), Nat. Immun. 6, 371.

    Loeffler, C., Berger, S., Durand, T., Bringmann, G., Dreyer, M., von Rad, U., Durner, J., Mueller, M.J. (2005) B1-phytoprostanes trigger plant defence and detoxification responses.
    Plant Physiol. 137, 328-340.

    Iqbal, M., Evans, P., Lledó, A., Verdaguer, X., Pericás, M.A., Riera, A., Loeffler, C., Sinha, A.K., Mueller, M.J. (2005) Total synthesis and biological activity of 13,14-dehydro-12-oxo-phytodienoic acids (deoxy-J1-phytoprostanes).
    Chem. Bio. Chem. 6, 276-280.

    von Rad, U., Mueller, M.J., Durner, J. (2005) Evaluation of natural and synthetic stimulants of plant immunity by microarray technology.
    New Phytologist 165, 191-202.
     

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